Does Bone Marrow Transplant Cure Sickle Cell?

Yes, a bone marrow transplant can cure sickle cell disease.   

A bone marrow transplant, also known as a stem cell transplant, is a medical procedure that replaces damaged or destroyed bone marrow with healthy bone marrow. Bone marrow is the spongy tissue inside your bones that produces blood cells. In people with sickle cell disease, the bone marrow produces abnormal red blood cells that are shaped like sickles, or crescent moons. These sickle cells can get stuck in small blood vessels, which can cause pain and other health problems.  

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During a bone marrow transplant, the patient's own bone marrow is destroyed with chemotherapy or radiation therapy. Then, healthy bone marrow from a donor is transplanted into the patient. The donor is usually a close relative, such as a sibling, who has a matching tissue type.   

If the bone marrow transplant is successful, the patient's body will start to produce healthy red blood cells. This can cure sickle cell disease and prevent further health problems. Bone marrow transplant is a complex and risky procedure. It is usually only recommended for people with severe sickle cell disease who have not responded to other treatments.

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